Elisabeth Nyström Lab
Mucus from molecule to man
Dissecting mucus function to uncover disease mechanisms and treatments
Mucus is, in our opinion, a wonderful, complicated and an often neglected component of our mucosal defense systems. It lies at the interface of our mucosal surfaces and our surrounding. It dictates our immediate interaction with agents from the environment, both beneficial and harmful. However, despite its relevance in several acute and chronic mucosal diseases, we lack a clear understanding of how mucus works.
By understanding the fundamental biochemistry, biology and physiology related to mucus, we aim to find out what goes wrong in disease and find ways to correct it.
Elisabeth Nyström, PI
MPharm, PhD
I am a biomedical researcher specializing in the biology of mucus and its role in gut health and disease. My work combines advanced imaging, proteomics, and translational models, with strong emphasis on collaborative and interdisciplinary research. My findings have helped reshape understanding of mucus in both health and inflammation, and provide a foundation for future discoveries in mucosal biology.
My PhD work focused on the protease CLCA1 and its impact on colonic mucus structure and function, revealing how post-translational modifications shape the mucus barrier.
During my postdoctoral research at Kiel University and University of Gothenburg, I explored how mucus dysfunction contributes to ulcerative colitis, and uncovering previously unknown diversity among mucus-producing goblet cells.
Open positions
The lab is looking for undergraduates, PhD candidates and postdocs to join ongoing projects — get in touch if you'd like to be part of the team.
Potential candidates should contact Elisabeth for more details. Please include a cover letter (max 1 page of A4), CV and up to 2 references.
